Riders set out one by one in the suspenseful final time trial in the Tour de France, with Cadel Evans or one of the Schleck brothers most likely to take home the yellow jersey.

Andy Schleck of Luxembourg held a 53-second lead over older brother Frank, and a 57-second gap on Australia's Evans - seen as the best time-trial rider among the three.

The riders compete in the time trial in reverse order of the overall standings, so the contenders hit the course last.

World timetrial champion Fabian Cancellara of Switzerland was the early leader, finishing the 26.4-mile race against the clock in 57 minutes, 15 seconds. His teammates, the Schleck brothers, were in the car that followed him, taking a look at the course before their rides.

"I did the maximum. I think I couldn't do more," said Cancellara, who had been unable to check out the course before he rode because of traffic delays on the road from Alpe d'Huez.

Although there is one more stage, the leader after the time trial was almost certain to be the overall victor: Sunday's finale on the Champs-Elysees in Paris tends to be ceremonial, because launching a successful attack on that flat last stage is virtually impossible.

Cancellara thought Andy Schleck had a good chance.

"Of course Cadel is very, very good, but we had three hard days in the Alps and it's simply man against man today, and the strongest will probably win the tour now," he said.

Alberto Contador of Spain, the defending champion, made a last-ditch push Friday in the final ride in the Alps, but came up short: his three-peat bid all but over.

In the time-trial of the Criterium du Dauphine stage race last month - the exact same one as Saturday's - Evans placed sixth against some of the world's best time-trialers, and was 1:20 back of winner Tony Martin.

Andy Schleck wasn't there. In the final time trial in last year's Tour, he placed 44th - 6:14 behind winner Fabian Cancellara - but only 31 seconds slower than Contador, one of the world's top time trialers. Evans was more than 4½ minutes slower, but was out of race contention then.

In the 2008 Tour, Evans was nearly 2 minutes faster than Andy in a time trial that was about 6 miles longer. But that was his first Tour, he was only 23, and has worked to improve his time-trial skills.

"Fifty-seven seconds, well, that's a minute - it's a lot, even if he is a specialist," Andy said Friday. "I'm not a specialist. But the yellow jersey on your shoulders, it gives you wings."

France's Thomas Voeckler, whose 10-day run in yellow was snapped by Andy Schleck on Friday, was fourth, 2:10 back. Italy's Damiano Cunego was fifth, 3:31 back, and Contador was sixth, 3:55 behind.

The parallels between Andy and Evans are considerable. They're both two-time runners-up. They've both been second to Contador - Evans once and Schleck twice - and each know what it's like to just barely miss out on victory. Evans was second to Contador by 23 seconds in 2007; Schleck was 39 seconds behind the Spaniard last year - two of the closest finishes in the 108-year history of the race.

Evans, of the U.S. team BMC, would be the first Australian winner. Schleck - whichever one - would be the first Luxembourg rider since Charly Gaul was the first and only from winner from that country to win, in 1958.

Andy says it has been a childhood dream to be on the podium with his older brother: "First and second a day before Paris: what more could anyone want? ... We're here. But we know it's not finished. We're both motivated."

No brothers have ever shared a Tour de France podium.

Voeckler lost the coveted yellow shirt to Andy Schleck on Friday after cracking on the day's first climb - and couldn't catch up on the famed Alpe d'Huez finish in Stage 19, won by Europcar teammate Pierre Rolland.

"My motivation is super, my legs are good, my condition is there, so I'm confident I can keep this till Paris," Andy said of the leader's tunic.

Evans' formula for capturing it?

"Start as fast as possible. Finish as fast as possible. Hope you're fast enough," he said.